Bioinformatics of glycosaminoglycans

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Glycosaminoglycans Metabolism

1Department of Surgical and Morphological Sciences, University of Insubria, via J.H. Dunant 5, 21100 Varese, Italy 2Department of Biomaterials, Radboud University Medical Center Nijmegen, 6500 HB Nijmegen, The Netherlands 3Polymer Chemistry and Biomaterials (PBM) Group, Department of Organic Chemistry, Ghent University, Krijgslaan 281 S4, 9000 Ghent, Belgium 4Gene Therapy Laboratory, Liver Unit...

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The sugar components of acidic glycosaminoglycans have long been known to be derived from glucose without alteration of the sugar ring (Topper & Lipton, 1953). The discovery of the nucleotide sugars by Caputto et al. (1950) and Park (1952) radically transformed the outlook on the biosynthesis of polysaccharides. It became rapidly apparent, not only that nucleotide sugars were the ‘activated’ do...

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Glycosaminoglycans and Proteoglycans

In this editorial to MDPI Pharmaceuticals special issue "Glycosaminoglycans and Proteoglycans" we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan, serglycin, cell-surface proteoglycans, like syndecans and glypicans, and the extracellular matrix proteoglycans, like aggrecan, perlecan, and ...

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Glycosaminoglycans and infection.

Glycosaminoglycans (GAGs) are complex linear polysaccharides expressed in intracellular compartments, at the cell surface, and in the extracellular environment where they interact with various molecules to regulate many cellular processes implicated in health and disease. Subversion of GAGs is a pathogenic strategy shared by a wide variety of microbial pathogens, including viruses, bacteria, pa...

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of glycosaminoglycans in chicken eggs

Glycosaminoglycans (GAGs) have numerous applications in the fields of pharmaceuticals, cosmetics, nutraceuticals, and foods. GAGs are also critically important in the developmental biology of all multicellular animals. GAGs were isolated from chicken egg components including yolk, thick egg white, thin egg white, membrane, calcified shell matrix supernatant, and shell matrix deposit. Disacchari...

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ژورنال

عنوان ژورنال: Perspectives in Science

سال: 2017

ISSN: 2213-0209

DOI: 10.1016/j.pisc.2016.01.014